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The results were quantified using a discrimination index (DI), representing the duration of exploration for the novel object compared to the old object

Continuous data collected from the participants over the 26 week treatment period was assessed using an ANCOVA model, using randomized treatment as a factor and baseline bodyweight as a covariate

Compared to placebo, ALC produced a significant pain reduction equal to 20.2% (95% CI: 8.3%-32.1%, P 50% indicated a statistically significant among-study heterogeneity: in this case, studies were pooled using random-effects model

No significant differences were observed in abdominal visceral fat or total fat mass