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doi: 10.1016/j.heliyon.2021.e06734 153 NguyenNQNguyenMTNguyenVTLeVMTrieuLHLeXTet al

RCT conducted in patients with T2D showed that high doses of tirzepatide represent the most efficacious incretin-based anti-diabetes drug in terms of BW reduction 33 , sustaining the development of the SURMOUNT program to explore its efficacy and safety in the management of obesity 9