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Notably, it appears to preferentially affect cancerous cells while minimizing harm to normal tissues, suggesting a more targeted therapeutic profile

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mTORC2 is mainly composed of mTOR, Rictor, mSin1, Protor-1, mLST8, and Sik3

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Glutamine: Pleiotropic roles in tumor growth and stress resistance

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For instance, in melanoma, miR-9 targeted GOT1 directly, inhibiting the expression of GOT1, which suppressed ferroptosis of melanoma cells (76)

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