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Description

The E3 ubiquitin protein ligase FBW7 (F-box and WD40 repeat domain-containing 7) binds to and degrades telomeric protection protein 1 (TPP1), which leads to telomere uncapping and induces senescence and fibrosis [61]

Intracutaneous testing, also called intradermal testing, for the diagnosis of food allergy is not recommended given the risk of serious adverse reactions [2]