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If the product used in these NTP studies was indeed kava root powder, the results need to be interpreted again with caution because the powder, administered whole and directly to the rodents, is substantially different from the traditional and anxiolytic kava forms that humans use

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Anthracyclines (doxorubicin, epirubicin) inflict double-stranded breaks through topoisomerase-II poisoning and redox cycling, while taxanes (paclitaxel, docetaxel) arrest microtubule dynamics, inducing mitotic catastrophe in growing follicles