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The GSH under high water activity is not easy to save, only controlling the water activity below 0.3 to long-term stability

NMDARs are highly expressed in areas of the brain involved in regulating emotion, such as the hippocampus, where they play a pivotal role in synaptic plasticity and normal working memory, making their activity both necessary and potentially harmful

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In patients with MDD and in depressive models, the mRNA levels of FTO and m 6 A methyltransferases (METTL3, METTL14, and WTAP) are significantly down-regulated