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Growth Hormone Stimulation: It boosts growth hormone release without affecting cortisol levels

Marked dose-dependent effects on body weight and nitrogen retention were produced, with the highest IGF-I dose, 695 micrograms/day, giving a 6 g increase in body weight over 7 days, compared with a 19 g loss in the dexamethasone-only group and an 18 g gain in pair-fed controls

Researchers incorporated notoginsenoside and salvianolic acid B into an RGD-modified dual-drug delivery system

Its journey from promising hGH fragment to discontinued candidate underscores the complexity of translating preclinical findings into safe, effective human therapeutics