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SKU: 57154642695
Price: 24.09 USD
Availability: InStock
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Description

Rutin protects hair cells and spiral ganglion neurons from cisplatin-induced ototoxicity by reducing ROS production after cisplatin exposure, activating PI3K/AKT signalling and inhibiting the JNK/p38/MAPK signalling pathway (Zheng et al., 2022)

When intracellular glutathione levels are sufficient, this feedback mechanism suppresses further synthesis, preventing excessive accumulation of pathway intermediates