glutathione peroxidase 4 inhibits w Regulation of Ferroptotic Cancer Cell Death by GPX4: Cell The Selenoprotein Glutathione Peroxidase 4:

These additives are carefully selected to maintain isotonicity and prevent oxidative degradation

After Phase II, a final Phase III process can modify these xenobiotic conjugates in ways that enhance the linker molecules attraction for transport proteins which pump the metabolite out of the cell.4 While this may all seem complex, the net effect of the entire process is to transform a drug molecule into a less active yet more bulky and water-soluble metabolite which can be easily excreted

10.1186/s12917-020-02441-0 [DOI] [PMC free article] [PubMed] [Google Scholar] Li H., Zhang L., Zhang X., Zhu G., Zheng D., Luo S., et al

In addition, their high cost is a critical obstacle, as these treatments are generally unaffordable for most patients (117)