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In Jerne's own words the discovery 'deeply impressed' him and was key to his 'speculation about the mechanism of antibody formation.' Importantly it galvanised his realisation that antibodies 'are already there' without prior contact with an antigen (Sderqvist, 2003)

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And probably about 10 to 15 years ago, I got really interested in this integrative and functional world of nutrition, moving away from the standard calories in, calories out mentality that I was taught at school

Graded regulation of cellular quiescence depth between proliferation and senescence by a lysosomal dimmer switch