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Intracellular glutathione depletion by oridonin leads to apoptosis in hepatic stellate cells

doi: 10.7164/antibiotics.27.254, 91

In N-nitrosodiethylamine-induced hepatotoxicity, pretreatment of GEN (25, 50 and 100 mg/mL, orally) markedly relieved genotoxic damage, improved oxidative stress and reduced serum levels of blood serum enzymes (Ali et al., 2015)