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Description

Curcumin, an active component of turmeric (Curcuma longa), and its effects on health

Firstly, GA inhibited vascular calcification by blocking the BMP2-Smad1/5/8 signaling pathway.In vascular smooth muscle cells (VSMCs) induced by inorganic phosphate (Pi), GA inhibited vascular calcification by interfering with the osteogenic signaling pathway through suppressing BMP2 upregulation and Smad1/5/8 phosphorylation (Kee et al., 2014)