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Melasma is a common skin condition in which the body overproduces melanin, creating symmetrical dark brown patches of pigment typically on the face, forehead, upper cheeks, and around the mouth

Heffernan MA, Thorburn AW, Fam B, et al

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Moreover, more recently a family of proteins called peroxiredoxins has been recognized as catalyzing the reduction of H 2 O 2 by GSH and/or other thiols, but with cysteine in its thiolate form, in their active sites rather than selenium-cysteine (Strange et al., 2000)