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These are sulfur-containing molecules that catalyze the oxidative decarboxylation of alpha-keto acids, such as pyruvate and alphaketoglutarate, in the Krebs cycle

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Early clinical trials used intravenous dosing, but subcutaneous self-administration proved equally effective and more practical for extended protocols

These cells were then exposed to various stress-inducing agents, including menadione to induce oxidative stress, blue light, and pollutants, mimicking real-world environmental challenges