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Eight DEGs involving proteins were presented in purine/pyrimidine metabolism, among which the nucleoside diphosphate kinase (Ndk) is a housekeeping enzyme that functions to balance the cellular nucleoside triphosphate pool and was believed to regulate microbial virulence [72], showed a value of log2FC 2.80 at 3 DPI vs CK (Additional file 1: Dataset S1)

Too much can overstimulate neurons

Disclosures: Yuanji Ma: Nothing to Disclose, Fang Chen: Nothing to Disclose, Lingyao Du: Nothing to Disclose, Lang Bai: Nothing to Disclose, hong Tang: Nothing to Disclose 2099 ASSOCIATION BETWEEN SYSTEMIC IMMUNE-INFLAMMATION INDEX AND SHORT-TERM PROGNOSIS OF ACUTE-ON-CHRONIC LIVER FAILURE Yuanji Ma Fang Chen 1 Lingyao Du 1 Lang Bai 1 hong Tang 1 , 1 West China Hospital, Sichuan University Background: The systemic immune-inflammatory index (SII) has been identified as an independent prognostic factor for multiple diseases