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This unique modality of cell death, which is distinguishable from other nonapoptotic forms of RCD according to its morphological and biochemical features, is characterized by intracellular excessive lipid peroxide accumulation and iron metabolism disturbances (Galluzzi et al., 2018)

Interestingly, intravenous injections of glutathione have been used for years but there is not even a single clinical trial evaluating its efficacy

This section will highlight several key ferroptosis targets, as illustrated in Fig