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Description

Implications for prostate cancer of insulin-like growth factor-I (IGF-I) genetic variation and circulating IGF-I levels

Chen, S.-P

The output is a single annotated construct view: every potential cryptic site mapped, ranked by accessibility, with suggested point mutations (filtered through AstraDDG for stability impact) that abolish the cryptic site without destabilizing the protein

Several biologic therapies have been developed which block these immune cells, mainly cytokines (TNF-, IL-17, IL-1, IL-23, IL-36), Janus kinases, and chemokines (13)