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Nizamutdinova et al

We applied UnPaSt with binarization P value threshold of P = 0.05, direction = both (to identify biclusters consisting of both upregulated and downregulated clusters) and all other parameters set to default to image-level and patient-level cluster intensities

Considering the immunosuppressive microenvironment characterizing KRAS mutant cancers, results from clinical trials utilizing this mechanism are anxiously awaited