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Specifically, PYC improves endothelial function, microcirculation, and inflammatory marker profiles in patients recovering from symptomatic coronavirus disease-2019 (COVID-19) ( Given the increasing threat of emerging and re-emerging viral infections ( 2 Antioxidative effects of PYC PYC exhibits potent antioxidant properties by effectively scavenging reactive oxygen and nitrogen speciesincluding superoxide (O 2 ), nitric oxide (NO), peroxynitrite (ONOO ), and hydroxyl radicals (OH)thereby counteracting oxidative stress induced by excessive reactive oxygen species (ROS) production ( Following sepsis induction in Wistar albino rats, PYC treatment decreased malondialdehyde levels, increased GSH levels, and enhanced SOD and GPx activities

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More recently, evaluation of microbiome-mediated gut dysregulation provides insight into the peripheral etiology of neurodegenerative disorders such as PD and AD

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