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These include: Hemodialysis Hemodialysis also often involves blood transfusion and/or administration of erythropoietin or its analogs either of which also require a TUE Treatment for Sickle Cell Disease involves homologous blood transfusions which are prohibited If an athlete requires a Prohibited treatment involving the removal and reintroduction of blood into the circulation for any legitimate medical condition, they should apply for a Therapeutic Use Exemption (TUE) before undergoing the treatment

The available research consists primarily of preclinical studies in animal models and in vitro cellular studies

Table 1: Patient Risk Factors Associated with B 12 Deficiency Bold represents factors associated with more rapid onset of clinical symptoms i.e., within 5 years

Those early results generated considerable excitement