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PCSK9 inhibitors primarily include monoclonal antibodies (e.g., alirocumab and evolocumab) and small interfering RNA (e.g., inclisiran)

Given this, the only official ASCO recommendation is that clinicians should carefully assess the risks and benefits of chemotherapy drugs known to cause CIPN, particularly in patients with pre-existing neuropathy or conditions that increase neuropathy risk, such as diabetes or a family history of neuropathy

Belardi V, Gallagher EJ, Novosyadlyy R, LeRoith D

Ecotoxicol Environ Saf 52:199223 Pigna M, Cozzalino V, Violante A, Meharg AA (2009) Influence of phosphate on the arsenic uptake by wheat ( Triticum durum L.) irrigated with arsenic solutions at three different concentrations