propionyl l carnitine acetyl l carnitine and lipoic acid Spring Valley L-Carnitine HCl Alpha Dietary Supplement, 50 Count Solaray Aceteyl L-Carnitine Alpha Lipoic

Tannir et al., CANTATA: Randomized, international, double-blind study of CB-839 plus cabozantinib versus cabozantinib plus placebo in patients with metastatic renal cell carcinoma. J Clin Oncol

Dark spots on hands: Daily SPF, consider topical vitamin C or niacinamide

Human Neutrophil elastase responsive delivery from poly(ethylene glycol) hydrogels

Promising strategies that move beyond symptomatic management include mitochondria-targeted antioxidants (e.g., MitoQ, SS-31), DRP1 inhibitors (e.g., Mdivi-1), NAD + boosters (e.g., nicotinamide riboside, nicotinamide mononucleotide), and gene-editing techniques for mutations in genes such as LRRK2 and HTT