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Dimethyl sulfoxide combined with intravesical cocktail therapy can lead to better outcomes after treatment, more effective reduction of inflammation, and higher quality of life for patients with interstitial cystitis.7 Other therapies for interstitial cystitis include injecting or infusing hyaluronic acid, botulinum toxin A, triamcinolone, resiniferatoxin, and platelet-rich plasma

You can minimize it by waiting a few seconds before withdrawing the needle.

Vitamin B12 should not be taken by children, pets, those who are pregnant or breastfeeding, or those who are allergic to any of the ingredients in vitamin B12 (Methylcobalamin)