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Symptoms can include difficulty breathing, swelling of the face or throat, and severe rash

Another mode of mast cell activation and degranulation involves the nervous system, with release of neuropeptides such as substance P, gastrin, vasoactive intestinal peptide (VIP), somatostatin, endorphin, and opioid peptides

Selenium is a cofactor for the enzyme glutathione peroxidase, which converts reduced glutathione to oxidized glutathione, which protects cells

The minimization procedure was performed sequentially by constraining the solute while minimizing water molecules, then constraining counterions, and finally minimizing the entire system without constraints