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Lopez A, Harada K, Chen HC, Bhutani MS, Weston B, Lee JH, Maru DM, Chin FW, Rogers JE, Thomas I, Amlashi FG, Blum-Murphy MA, Rice DC , Zhao M, Hofstetter WL, Nguyen Q, Ajani JA

RNA sequencing of giredestrant and palbociclib treated cells, and proteomic analysis of palbociclib treated cells identified pathways consistent with oxidative stress and increased lipid peroxidation (Fig

Therefore, considering future clinical application, CIBB might be more advantageous than CXCL10 antibody as it can effectively protect NRTP-induced ovary damage while not interfering with other regular tumor therapies

In summary, CoQ10 supplementation has demonstrated considerable potential in enhancing female fertility, particularly by improving ovarian function, increasing egg quality, and mitigating inflammatory responses (Figure 2)