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This limits the time for sample to interact with the resin resulting in insufficient binding, and, hence, inefficient protein purification

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Structure of GPX4 U46C-R152H is modeled based on PDB structure 2OBI

Since AOMs are indicated in combination with lifestyle interventions, all participants received dietary and physical activity counseling, aiming to achieve a 500-kcal deficit per day and 150 minutes of physical activity per week