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10.2174/1573401316999200614164711 48 DetailleD.PasdoisP.SmontA.SantosP

MDSCs) and may function as a protumourigenic and Tcell suppressor in the TME

This substantially inhibits the expression of two pivotal osteoclastogenic genes, TRAF6 and NFATc1, resulting in a considerable decrease in serum levels of bone resorption markers (105)