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Circulation 89 , 355360 (1994)

CrossRef Anxiolytic effects of -oryzanol in chronically- stressed mice are related to monoamine levels in the brain Salina Akter, Hiroyuki Sasaki, Kazi Rasel Uddin, Yuko Ikeda, Hiroki Miyakawa, Shigenobu Shibata Life Sciences.2019

Benefits: Improvement of symptoms associated with mold toxicity, biotoxin illness, and exposure to water-damaged buildings Decrease in symptoms related to chronic inflammation and Chronic Inflammatory Response Syndrome (CIRS) Improvement during respiratory failure related to Severe Acute Respiratory Syndrome (SARS) by binding to lung epithelial cells critical for oxygen transfer and surfactant production Reduction in mast cell activation Improved function of gut immune cells in Inflammatory Bowel Disease (IBD) Side-effects: Well-tolerated with few side-effects

It is a protein (enzyme) made by the gene of same name, both involved in the processing of folate