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If the answer to both is no, they will continue to up-titrate the dose by 2.5 mg every 4 weeks until reaching the next weight loss maintenance dose

This article will focus on the type of patients or medical conditions that may require the supplementation of vitamin B12 (see the table below).1-6 More importantly, it is necessary to recognize the reason that some of these patients require supplementation, including those using vitamin B12 in different dosage forms other than those to be taken by mouth

According to the American Heart Association, about 8.5 million people in the United States have PAD, and leg pain is often their first warning sign

Statements Author contributions ZM: data collection and writing the manuscript