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A-Kinase Anchor Protein 1 deficiency causes mitochondrial dysfunction in mouse model of hyperoxia induced acute lung injury

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Since excessive endothelial apoptosis may contribute to vascular disease, 45 it is possible that albumins protective effect on the vascular endothelium is due to its antiapoptotic activity.9, 37 Albumin may directly influence vascular integrity, by binding to the interstitial matrix and subendothelium and altering the permeability of these layers to large molecules and solutes