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Topical peptides have been well-studied and have an established safety profile because they act primarily at the skins surface and have minimal systemic exposure

A subsequent combination of the modelling of the pre-trained and the post-trained deep learning algorithm leads to an overall accuracy of 86%

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Comment: Commenters were supportive of the technical change that would remove the term grandfathered from applicable regulation texts and replace it with historically excepted. Response: We thank commenters for their support