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This process begins with the oxidation of N-terminal Cys2 and then proceeds with arginylation and proteasomal breakdown

As demonstrated, PPP activation not only regulates the expression of Axl and MerTK but also supplies NADPH to sustain redox homeostasis under efferocytic stress but also regulates the expression of apoptotic cell sensors and maintains membrane fluidity, features that are intrinsically linked to efficient efferocytosis [89] (Fig

These two classes are the most abundant in plants

subsequently showed that NADH and succinate could decrease the tocopheroxyl radical in mitochondria, therefore converting CoQ10 to its ubiquinol form [115]