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Neurotrauma 39 , 211226 (2022)

Research-domain overlap Where the two compounds appear in similar literature contexts: Both have been studied in tendon and ligament repair research models Both have been studied in angiogenesis research Both appear in research interest around musculoskeletal tissue repair Where they diverge: BPC-157 has more research literature on gastrointestinal repair models TB-500 has more research literature on cardiovascular cell biology and dermal wound research The two are not equivalent

Given the diverse roles played by O-GlcNAcylation in key cellular processes, much needs to be identified with respect to O-GlcNAcylated neuronal proteins, their O-GlcNAcylation sites, and the brain-specific signaling mechanisms selectively affected by O-GlcNAc modification