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Endocrinology 2010;151:1019-29

Figure 1 The key to understanding PEM lies in elucidating why exercise, which is generally protective in healthy individuals, induces pathological exacerbation in patients with PEM ( Thus, our study aims to synthesize pathophysiological evidence of energy metabolism, immune inflammation, and neurovascular system abnormalities observed following physical or cognitive exertion

Final sequence optimization: once peptide length and stapling strategies are finalized, peptide properties may be further optimized through sequence exploration

Ubiquitin-proteasome pathway in skeletal muscle atrophy