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TNF- can make quiescent hepatocytes more sensitive to growth factors, early elevation of TNF- during APAP toxicity may be an important factor in stimulating hepatocytes and promoting late liver regeneration [225]

FcRn antagonists may also be used in combination with other specific treatment regimens, for instance, targeting activation of complement and/or immune cells in diseases with a high inflammatory burden, to further improve the therapeutic outcome

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Critical as well as deceased COVID-19 patients demonstrate significantly lower serum levels of EPO, haptoglobin, and hepcidin compared to survivors or mild cases 439