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Future research should incorporate larger, multicenter, prospective studies with control groups to validate these preliminary findings, assessing the broader applicability of CO laser therapy for postoperative pillar pain, and account for potential confounding variables, such as concurrent occupational therapist or PT therapies, to achieve a more definitive conclusion

The X-ray crystal structure of the K1 domain shows that its tertiary structure is made up of a series of loops stabilized by three disulfide bonds 48 (Fig