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10.1007/s00403-007-0806-1 100 ImokawaG.YadaY.MorisakiN.KimuraM

Int J Biol Sci 15(3):544555

The study also revealed nonlinear pharmacokinetics, with dose-dependent increases in exposure and changes in clearance, indicating potential target-mediated drug disposition (TMDD) for AZD3965 [102]