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Mechanism-based combination strategies for enhancing ADC efficacy Although many ADCs exhibit superior monotherapy efficacy compared with conventional chemotherapy, their long-term therapeutic durability is frequently constrained by the emergence of resistance mechanisms, immune evasion, and dose-limiting toxicities [566571]

Hence, the supply of serine is critical for the availability of both precursors

Furthermore, the positive effects of dietary antioxidants, such as caffeic acid and vitamin E, on MASLD are being investigated [141, 160]