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While Tirzepatide often produces greater total weight loss than AOD-9604 , it also carries a more complex side effect profile including nausea, vomiting, and gastrointestinal distress

The term hydroxy or hydroxyl as used herein by itself or as part of another group refers to an OH group

Another concept is to measure B12 bound to the plasma protein transcobalamin (holoTC, active B12) before and after administration of three high physiological doses of B12 for two days