cornus fruit glutathione Frontiers Frontiers | Therapeutic mechanisms of

2023 Jun;38(6):1184-1193.e2

Tumor necrosis factor-alpha mediates activation of NF-kappaB and JNK signaling cascades in retinal ganglion cells and astrocytes in opposite ways

Polycystic ovarian syndrome is linked to increased oxidative stress in Omani women

Introduction Glutathione S -transferases (GSTs) are a family of enzymes that conjugate reduced glutathione (GSH) to target molecules in the phase II detoxification of xenobiotic metabolism ( Here we examined the mechanisms of how GSTM1 regulates astrocyte transcriptional program in response to pro-inflammatory signaling and further addressed the impact of GSTM1 loss-of-function on neurons during acute brain inflammation following a systemic injection of lipopolysaccharides (LPS)