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Wang et al., A reduction-degradable polymer prodrug for cisplatin delivery: preparation, in vitro and in vivo evaluation

They had ad libitum access to standard rodent chow and tap water throughout the study

Results of the screening with the use of the CAGF cloning method are consistent with the crystallographic data

As the complex, high-risk nature of Class-2 CTGTP requires proactive and strategic planning for full-filing evolving regulatory requirements throughout the product life cycle