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doi: 10.1053/j.gastro.2011.12.061 21 KlingensmithNJCoopersmithCM

In a diabetic retinopathy model, AST treatment elevated the levels of the antioxidant enzyme heme oxygenase-1 (HO-1) and preserved homeostasis for retinal ganglion cells (Figure 1, which illustrates ASTs modulation of key pathways such as Nrf2/ARE, PI3K/Akt, and NF-B in promoting neuroprotection

This innovative approach aims to enhance patient care by integrating genetic insights into personalized treatment plans

Looking ahead, establishing collaborative research platforms and promoting active engagement among experts across diverse fields will be key to driving future advancements in target discovery