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The administration of metformin and chloroquine increased the efficacy of cytarabine in suppressing NALM-6 cells, leading to decreased colony formation, increased apoptosis, and G1 phase cell cycle arrest

Similar to IBD patients, AS patients have lower blood MAIT cell levels than HCs, possibly due to the recruitment of MAIT cells to inflammatory sites such as the gut and joints ( The gut microbiota also stimulates DCs to secrete CXCL13, TGF-, and B-cell activating proteins, leading to immunoglobulin A (IgA) production and class switching by mucosal plasma cells

Graber W, Deboever N, Niu J, Eisenberg M, Antonoff M, Hofstetter W, Mehran R, Roth J , Sepesi B, Swisher S, Walsh G, Vaporciyan A, Giordano S, Rajaram R, Rice D

For example, Kras G12D released from autophagy-dependent ferroptotic cancer cell death can limit the antitumour effects of macrophages by activating STAT3-mediated AGER-dependent M2 macrophage polarization [114]