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If and how ROS regulate the pro- and/or anti-inflammatory response of macrophages depends on various factors, such as the source and compartmentalization of the ROS and the respective stimulus [36,234,306]

In thymine, OH abstracts a methyl hydrogen at the 5-position, generating a resonance-stabilized carbon radical that, upon oxygen addition and reduction, yields a hydroxymethylene derivative (Zheng et al., 2018)