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Although the newest imaging may suggest brain damage after mild traumatic brain injury (mTBI) (Mayer et al., 2010), the committee concluded that there is not enough data yet to demonstrate that the results of imaging can be used as accurate markers of outcome

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While this putative kinetically stabilising site has been suggested for drug discovery 28,35 , our findings nonetheless suggest alternative frameworks in the context of filament formation (instead of the previously suggested tetrameric state) that should be considered for targeting the CBS regulatory domain (discussed below)

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