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This model is supported by evidence from various experimental systems, including the ability of lactate to sustain synaptic function in vitro (Schurr et al., 1988), the cellular localization of relevant transporters and enzymes, and in vivo studies using microsensors that report rapid lactate consumption coupled to oxygen utilization in the tissue parenchyma during activation (Hu and Wilson, 1997)

Mepolizumab (brand name Nucala , manufactured by GlaxoSmithKline) is an IL-5 inhibitor that works differently than traditional asthma medications

They occur naturally in the body and play a vital role in hormone production, including stimulating human growth hormone (HGH)

doi: 10.1038/s41598-018-19213-4