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The first nootropic to use the term was a drug developed in the 1960s called piracetam.60 61 It was intended to treat anxiety and provide patients with a soothing experience that might even lull them to sleep.2 The effect was quite different than what its creators intended, as users reported sharper focus, and later testing pointed toward improved memory

Researchers started working with peptides in the 1920s, and synthetic peptides have been used to treat diabetes ever since

It also significantly reduced inflammatory markers TNF-alpha and destructive enzymes MMP-2/MMP-9

is a Professor Emerita, Departments of Physiology and Medicine at the University of Toronto, Toronto, ON, Canada