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Serum BDNF levels are consistently lower in patients with major depressive disorder compared to healthy controls, and successful antidepressant treatment normalizes these levels

Saccharolytic fermentation generates short-chain fatty acids (SCFAs) like acetate, propionate, and butyrate, which promote gut health and influence liver metabolism, potentially mitigating fat accumulation

Weight of evidence: Overall evidence is Moderate : randomized data show improved cellular GSH with selective functional gains

System biology-based assessment of the molecular mechanism of IMPHY000797 in Parkinsons disease: a network pharmacology and in-silico evaluation