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A separate study by Annesley et al

To better understand the mechanism of action of Avne thermal water in the treatment of AD, various pharmacological interventions have reported its anti-inflammatory effects, pathogenic skin microbiome alterations to nonpathogens, keratinocyte differentiation, and cytokine immunomodulatory effects (Guerrero & Garrigue 2017

Supports a more even skin tone with regular use

The alkyl radical in the presence of oxygen is converted to peroxyl radicals which facilitate the long-term damage by continually regenerating themselves through hydrogen abstraction from the nearby biomolecules and forming the hydroperoxides as the byproduct (Fig