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For instance, L-DON prevents the induction of PPAT and PAICS by glutamine and the reduction of pyruvate kinase activity [87] (Fig

doi: 10.3389/fnut.2022.746881 33 AbebeBKAlemayehuMT

Thus, these data indicate that decreased lipid accumulation by GSH depletion is primarily due to diminished lipogenesis rather than increased fatty acid utilization